ソフトウェア

ホモロジー検索等

blast 　Sequence Similarity Search
blast+
fasta

blat [1] BLAT on DNA is designed to quickly find sequences of 95% and greater similarity of length 25 bases or more

遺伝子情報取得

dbget　DBGET is an integrated database retrieval system for major biological databases

分子生物学用ソフトウェアパッケージ

EMBOSS [2] EMBOSS is a free Open Source software analysis package specially developed for the needs of the molecular biology

マルチプルアラインメント

clustalw　Multiple Sequence Alignment
clustalw2

muscle [3] Multiple Sequence Alignment faster and more accurate than clustalw

mafft [4] MAFFT is a multiple sequence alignment program

t_coffee [5]  Multiple sequence alignment package

Gblocks  [6] eliminates poorly aligned positions and divergent regions of an alignment of DNA or protein sequences

アセンブラー

CAP3 [7] Multiple Sequence Alignment
TGICL [8] Multiple Sequence Alignment (for huge data set)

Phred [9] The phred software reads DNA sequencing trace files, calls bases, and assigns a quality value to each called base

Phrap　Phrap is a program for assembling shotgun DNA sequence data

consed　Assembly Editor

次世代シーケンサデータ解析用

samtools [10] SAM Tools provide various utilities for manipulating alignments in the SAM format

bamtools [11] Bamtools is a toolkit for analyzing and managing BAM files

bwa [12] Burrows-Wheeler Aligner (BWA) is an efficient program that aligns relatively short nucleotide sequences against a long reference sequence

soap [13] Short Oligonucleotide Analysis Package

bowtie [14] Bowtie is an ultrafast, memory-efficient short read aligner
tophat [15] TopHat is a fast splice junction mapper for RNA-Seq reads
cufflinks [16] Cufflinks assembles transcripts, estimates their abundances, and tests for differential expression and regulation in RNA-Seq samples

trinityrnaseq [17] Novel method for the efficient and robust de novo reconstruction of transcriptomes from RNA-seq data

次世代シーケンサデータ解析用：アセンブラー

velvet [18] Sequence assembler for very short reads

abyss [19] Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler

allpaths-lg [20]  The new short read genome assembler

denovo2

遺伝子領域予測

genemark [21] A family of gene prediction programs

genscan [22] Gene prediction

glimmer [23] Glimmer is a system for finding genes in microbial DNA

augustus [24] AUGUSTUS is a program that predicts genes in eukaryotic genomic sequences

モチーフ検索

hmmer [25] Biosequence analysis using profile HMM

meme [26] Multiple Em for Motif Elicitation

系統樹解析

mrbayes [27] MrBayes is a program for Bayesian inference and model choice across a wide range of phylogenetic and evolutionary models

njplot [28] NJplot is a tree drawing program

paup [29] Tools for inferring and interpreting phylogenetic trees

phylip [30] A package of programs for inferring phylogenies (evolutionary trees)

phyml [31] PhyML is a phylogeny software based on the maximum-likelihood principle

tree-puzzle [32] Program to reconstruct phylogenetic trees from molecular sequence data by maximum likelihood

lastz

• インストール済みソフトウェア（その他）

Gene Spring 　（端末室 Windowsマシン上　所内のみ利用可）
MATLAB　（同上）
MATLAB Distributed Computing Server

• 他一般ソフトウェア、プログラム言語

csh
tcsh
zsh
bash
perl
ruby
python
gcc
icc 　(Intel Compiler)
mpicc