ソフトウェア

ホモロジー検索等

blast 　Sequence Similarity Search
blast+
fasta

blat [1] BLAT on DNA is designed to quickly find sequences of 95% and greater similarity of length 25 bases or more

遺伝子情報取得

dbget　DBGET is an integrated database retrieval system for major biological databases

分子生物学用ソフトウェアパッケージ

EMBOSS [2] EMBOSS is a free Open Source software analysis package specially developed for the needs of the molecular biology

マルチプルアラインメント

clustalw　Multiple Sequence Alignment
clustalw2

muscle [3] Multiple Sequence Alignment faster and more accurate than clustalw

mafft [4] MAFFT is a multiple sequence alignment program

t_coffee [5]  Multiple sequence alignment package

Gblocks  [6] eliminates poorly aligned positions and divergent regions of an alignment of DNA or protein sequences

アセンブラー

CAP3 [7]　Multiple Sequence Alignment
TGICL [8] Multiple Sequence Alignment (for huge data set)

Phred [9] The phred software reads DNA sequencing trace files, calls bases, and assigns a quality value to each called base

Phrap　Phrap is a program for assembling shotgun DNA sequence data

consed　Assembly Editor

次世代シーケンサデータ解析用

samtools [10] SAM Tools provide various utilities for manipulating alignments in the SAM format

bwa [11] Burrows-Wheeler Aligner (BWA) is an efficient program that aligns relatively short nucleotide sequences against a long reference sequence

soap [12] Short Oligonucleotide Analysis Package

abyss [13] Assembly By Short Sequences - a de novo, parallel, paired-end sequence assembler

allpaths-lg [14]  The new short read genome assembler

bowtie [15] Bowtie is an ultrafast, memory-efficient short read aligner
tophat [16] TopHat is a fast splice junction mapper for RNA-Seq reads
cufflinks [17] Cufflinks assembles transcripts, estimates their abundances, and tests for differential expression and regulation in RNA-Seq samples

trinityrnaseq [18] Novel method for the efficient and robust de novo reconstruction of transcriptomes from RNA-seq data

velvet [19] Sequence assembler for very short reads

denovo2 

遺伝子領域予測

genemark [20] A family of gene prediction programs

genscan [21] Gene prediction

glimmer [22] Glimmer is a system for finding genes in microbial DNA

モチーフ検索

hmmer [23] Biosequence analysis using profile HMM

meme [24] Multiple Em for Motif Elicitation

系統樹解析

mrbayes [25] MrBayes is a program for Bayesian inference and model choice across a wide range of phylogenetic and evolutionary models

njplot [26] NJplot is a tree drawing program

paup [27] Tools for inferring and interpreting phylogenetic trees

phylip [28] A package of programs for inferring phylogenies (evolutionary trees)

phyml [29] PhyML is a phylogeny software based on the maximum-likelihood principle

tree-puzzle [30] Program to reconstruct phylogenetic trees from molecular sequence data by maximum likelihood

lastz

• インストール済みソフトウェア（その他）

Gene Spring 　（端末室 Windowsマシン上　所内のみ利用可）
MATLAB　（同上）
MATLAB Distributed Computing Server

• 他一般ソフトウェア、プログラム言語

csh
tcsh
zsh
bash
perl
ruby
python
gcc
icc 　(Intel Compiler)
mpicc